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Professor David E JaneB.A.(Cantab.), Ph.D.(Salf.), M.R.S.C.

Professor in Chemical Pharmacology

1 - 10 out of 75Page size: 10
  1. 2019
  2. Published

    Assembly and Trafficking of Homomeric and Heteromeric Kainate Receptors with Impaired Ligand Binding Sites

    Scholefield, C., Atlason, P., Jane, D. & Molnar, E., 1 Mar 2019, In : Neurochemical Research. 44, 3, p. 585-599 15 p.

    Research output: Contribution to journalArticle

  3. Published

    The 1980s: d-AP5, LTP and a Decade of NMDA Receptor Discoveries

    Lodge, D., Watkins, J. C., Bortolotto, Z., Jane, D. & Volianskis, A., 1 Mar 2019, In : Neurochemical Research. 44, 3, p. 516-530 15 p.

    Research output: Contribution to journalArticle

  4. Published

    Investigation of the structural requirements for N-methyl-D-aspartate receptor positive and negative allosteric modulators based on 2-naphthoic acid

    Irvine, M. W., Fang, G., Sapkota, K., Burnell, E. S., Volianskis, A., Costa, B. M., Culley, G., Collingridge, G. L., Monaghan, D. T. & Jane, D. E., 15 Feb 2019, In : European Journal of Medicinal Chemistry. 164, p. 471-498 28 p.

    Research output: Contribution to journalArticle

  5. Published

    Positive and Negative Allosteric Modulators of N-Methyl- d -aspartate (NMDA) Receptors: Structure-Activity Relationships and Mechanisms of Action

    Burnell, E. S., Irvine, M., Fang, G., Sapkota, K., Jane, D. E. & Monaghan, D. T., 10 Jan 2019, In : Journal of Medicinal Chemistry. 62, 1, p. 3-23 21 p.

    Research output: Contribution to journalArticle

  6. Published

    The NMDA receptor intracellular C-terminal domains reciprocally interact with allosteric modulators

    Sapkota, K., Dore, K., Tang, K., Irvine, M., Fang, G., Burnell, E. S., Malinow, R., Jane, D. E. & Monaghan, D. T., Jan 2019, In : Biochemical Pharmacology. 159, p. 140-153 14 p.

    Research output: Contribution to journalArticle

  7. 2018
  8. Published

    Putative Receptors Underpinning L-Lactate Signalling in Locus Coeruleus

    Mosienko, V., Rasooli-Nejad, A., Kishi, K., De Both, M., Jane, D., Huentelman, M., Kasparov, S. & Teschemacher, A., 16 Nov 2018, In : Neuroglia. 1, 2, p. 365-380 16 p.

    Research output: Contribution to journalArticle

  9. E-pub ahead of print

    Some distorted thoughts about ketamine as a psychedelic and a novel hypothesis based on NMDA receptor-mediated synaptic plasticity

    Ingram, R., Kang, H. H., Lightman, S., Jane, D., Bortolotto, Z., Collingridge, G., Lodge, D. & Volianskis, A., 6 Jun 2018, In : Neuropharmacology.

    Research output: Contribution to journalArticle

  10. 2017
  11. Published

    Mechanism and properties of positive allosteric modulation of N-methyl-d-aspartate receptors by 6-alkyl 2-naphthoic acid derivatives

    Sapkota, K., Irvine, M. W., Fang, G., Burnell, E. S., Bannister, N., Volianskis, A., Culley, G. R., Dravid, S. M., Collingridge, G. L., Jane, D. E. & Monaghan, D. T., Oct 2017, In : Neuropharmacology. 125, p. 64-79 16 p.

    Research output: Contribution to journalArticle

  12. Published

    A single-channel mechanism for pharmacological potentiation of GluN1/GluN2A NMDA receptors

    Chopra, D. A., Sapkota, K., Irvine, M. W., Fang, G., Jane, D. E., Monaghan, D. T. & Dravid, S. M., 31 Jul 2017, In : Scientific Reports. 7, 11 p., 6933.

    Research output: Contribution to journalArticle

  13. Published

    The Startle Disease Mutation E103K Impairs Activation of Human Homomeric α1 Glycine Receptors by Disrupting an Intersubunit Salt Bridge across the Agonist Binding Site

    Safar, F., Hurdiss, E., Erotocritou, M., Greiner, T., Lape, R., Irvine, M. W., Fang, G. Y., Jane, D., Yu, R., Dämgen, M. A., Biggin, P. C. & Sivilotti, L. G., 24 Mar 2017, In : Journal of Biological Chemistry. 292, 12, p. 5031-5042 12 p.

    Research output: Contribution to journalArticle

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