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Professor Jan FrayneB.Sc.(Nott.), Ph.D.(Bristol)

Professor in Molecular Cell Biology

1 - 10 out of 68Page size: 10
  1. 2019
  2. Published

    Vimentin expression is retained in erythroid cells differentiated from human iPSC and ESC and indicates dysregulation in these cells early in differentiation

    Trakarnsanga, T., Ferguson, D., Daniels, D., Griffiths, R., Wilson, M., Mordue, K., Andrienko, T., Condie, A., McCahill, A., Mountford, J. C., Toye, A., Anstee, D. & Frayne, J., 29 Apr 2019, In : Stem Cell Research and Therapy. 10, 10 p., 130.

    Research output: Contribution to journalArticle

  3. 2018
  4. E-pub ahead of print

    Enhancement of red blood cell transfusion compatibility using CRISPR‐mediated erythroblast gene editing

    Hawksworth, J., Satchwell, T., Meinders, M., Daniels, D., Regan, F., Thornton, N., Wilson, M., Dobbe, J. G. G., Streekstra, G. J., Trakarnsanga, K., Heesom, K., Anstee, D., Frayne, J. & Toye, A., 26 Apr 2018, In : EMBO Molecular Medicine. 10, 5, 11 p., e8454.

    Research output: Contribution to journalArticle

  5. Published

    Secretory factors from OP9 stromal cells delay differentiation and increase the expansion potential of adult erythroid cells in vitro

    Trakarnsanga, K., Wilson, M. C., Heesom, K. J., Andrienko, T. N., Srisawat, C. & Frayne, J., 31 Jan 2018, In : Scientific Reports. 8, 1, 8 p., 1983.

    Research output: Contribution to journalArticle

  6. Published

    Optimization of an Erythroid Culture System to Reduce the Cost of in vitro Production of Red Blood Cells

    Poldee, S., Metheetrairuta, C., Nugoolsuksiri, S., Frayne, J. & Trakarnsanga, T., 2018, In : MethodsX. 5, p. 1626-1632 7 p.

    Research output: Contribution to journalArticle

  7. 2017
  8. Published

    Activation of KLF1 enhances the differentiation and maturation of red blood cells from human pluripotent stem cells

    Yang, C-T., Ma, R., Frayne, J. & Forrester, LM., Apr 2017, In : Stem Cells. 35, 4, p. 886–897 12 p.

    Research output: Contribution to journalArticle

  9. Published

    An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells

    Trakarnsanga, K., Griffiths, R. E., Wilson, M. C., Blair, A., Satchwell, T. J., Meinders, M., Cogan, N., Kupzig, S., Kurita, R., Nakamura, Y., Toye, A. M., Anstee, D. J. & Frayne, J., 14 Mar 2017, In : Nature Communications. 8, 7 p., 14750.

    Research output: Contribution to journalArticle

  10. 2016
  11. Published

    Comparison of the proteome of adult and cord erythroid cells, and changes in the proteome following reticulocyte maturation

    Wilson, M., Trakarnsanga, K., Heesom, K., Toye, A. & Frayne, J., 1 Jun 2016, In : Molecular and Cellular Proteomics. 15, 6, p. 1938-1946 9 p.

    Research output: Contribution to journalArticle

  12. Published

    Krüppeling erythropoiesis: an unexpected broad spectrum of human red blood cell disorders due to KLF1 variants

    Perkins, A., Xu, X., Higgs, D., Patrinos, G. P., Arnaud, L., Bieker, J. J., Philipsen, S. & KLF1 Consensus Workgroup, 14 Apr 2016, In : Blood. 127, 15, p. 1856-1862 7 p.

    Research output: Contribution to journalArticle

  13. 2014
  14. Published

    Induction of adult levels of β-globin in human erythroid cells that intrinsically express embryonic or fetal globin by transduction with KLF1 and BCL11A-XL

    Trakarnsanga, K., Wilson, M. C., Lau, W. W. Y., Singleton, B. K., Parsons, S. F., Sakuntanaga, P., Kurita, R., Nakamura, Y., Anstee, D. J. & Frayne, J., 2014, In : Haematologica. Aug 8. pii: haematol.2014.110155.

    Research output: Contribution to journalArticle

  15. Published

    Qualitative and Quantitative Comparison of the Proteome of Erythroid Cells Differentiated from Human iPSCs and Adult Erythroid Cells by Multiplex TMT Labelling and NanoLC-MS/MS

    Trakarnsanga, K., Wilson, M. C., Griffiths, R. E., Toye, A. M., Carpenter, L., Heesom, K. J., Parsons, S. F., Anstee, D. J. & Frayne, J., 2014, In : PLoS ONE. 9, 7, p. e100874

    Research output: Contribution to journalArticle

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