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Professor M.Saadeh SuleimanPhD, DSc, FIACS, FRSB, FPhysiol

Professor of Cardiac Physiology

Saadeh Suleiman

Professor M.Saadeh SuleimanPhD, DSc, FIACS, FRSB, FPhysiol

Professor of Cardiac Physiology

Member of

Research interests

Current Research Projects (basic science/translational/clinical):

  1. Role of cyclic AMP/PKA/Epac signalling in cardioprotection
  2. The Cardiac Role of the Exchange Protein Directly Activated by cAMP (Epac) During Postnatal Development
  3. The cardio-protective efficacy of cardioplegic solution supplemented with Sildenafil in neonatal pig model of cardiopulmonary bypass and cardioplegic arrest
  4. Selective S-nitrosation of mitochondrial complex I by MitoSNO as a new therapy for cardiac ischaemia-reperfusion injury
  5. A Polymeric Prosthetic Heart Valve from anisotropic nanocomposites– device optimisation and in vivo testing           
  6. RIPC Clinical Trial: A two-centre randomised controlled trial investigating the effect of remote ischaemic preconditioning on biomarkers of stress and injury-related signalling in patients having isolated coronary artery bypass grafting or aortic valve replacement using cardiopulmonary bypass.
  7. Efficacy of propofol-supplemented cardioplegia on biomarkers of organ injury in patients having cardiac surgery using cardiopulmonary bypass: Propofol cardioplegia for myocardial protection randomised controlled trial: The Prompt2 Study.
  8. The role of cyclic-AMP/PKA/Epac signalling in cardioprotection of diseased heart (PhD project)
  9. The aged heart and diet: vulnerability to cardiac insults (PhD project)
  10. Cardiac survival signalling, oxidative stress & reperfusion injury during postnatal development (PhD project).

 

 

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Postal address:
Level 7
Bristol Royal Infirmary
Upper Maudlin Street
Bristol
United Kingdom

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