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Genetics of biologically based psychological differences

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Genetics of biologically based psychological differences. / Sallis, Hannah; Smith, George Davey; Munafò, Marcus R.

In: Philosophical Transactions B: Biological Sciences, Vol. 373, No. 1744, 20170162, 19.04.2018.

Research output: Contribution to journalArticle

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Sallis, H, Smith, GD & Munafò, MR 2018, 'Genetics of biologically based psychological differences', Philosophical Transactions B: Biological Sciences, vol. 373, no. 1744, 20170162. https://doi.org/10.1098/rstb.2017.0162

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Sallis H, Smith GD, Munafò MR. Genetics of biologically based psychological differences. Philosophical Transactions B: Biological Sciences. 2018 Apr 19;373(1744). 20170162. https://doi.org/10.1098/rstb.2017.0162

Author

Sallis, Hannah ; Smith, George Davey ; Munafò, Marcus R. / Genetics of biologically based psychological differences. In: Philosophical Transactions B: Biological Sciences. 2018 ; Vol. 373, No. 1744.

Bibtex

@article{121518a4a8484ef194cd383f83dc322f,
title = "Genetics of biologically based psychological differences",
abstract = "In recent years, substantial effort has gone into disentangling the genetic contribution to individual differences in behaviour (such as personality and temperament traits). Heritability estimates from twin and family studies, and more recently using whole genome approaches, suggest a substantial genetic component to these traits. However, efforts to identify the genes that influence these traits have had relatively little success. Here, we review current work investigating the heritability of individual differences in behavioural traits and provide an overview of the results from genome-wide association analyses of these traits to date. In addition, we discuss the implications of these findings for the potential applications of Mendelian randomization. This article is part of the theme issue ‘Diverse perspectives on diversity: multi-disciplinary approaches to taxonomies of individual differences’.",
keywords = "Behavioural traits, GWAS, Heritability, Mendelian randomization, Personality, Temperament",
author = "Hannah Sallis and Smith, {George Davey} and Munaf{\`o}, {Marcus R.}",
year = "2018",
month = "4",
day = "19",
doi = "10.1098/rstb.2017.0162",
language = "English",
volume = "373",
journal = "Philosophical Transactions B: Biological Sciences",
issn = "0962-8436",
publisher = "The Royal Society",
number = "1744",

}

RIS - suitable for import to EndNote

TY - JOUR

T1 - Genetics of biologically based psychological differences

AU - Sallis, Hannah

AU - Smith, George Davey

AU - Munafò, Marcus R.

PY - 2018/4/19

Y1 - 2018/4/19

N2 - In recent years, substantial effort has gone into disentangling the genetic contribution to individual differences in behaviour (such as personality and temperament traits). Heritability estimates from twin and family studies, and more recently using whole genome approaches, suggest a substantial genetic component to these traits. However, efforts to identify the genes that influence these traits have had relatively little success. Here, we review current work investigating the heritability of individual differences in behavioural traits and provide an overview of the results from genome-wide association analyses of these traits to date. In addition, we discuss the implications of these findings for the potential applications of Mendelian randomization. This article is part of the theme issue ‘Diverse perspectives on diversity: multi-disciplinary approaches to taxonomies of individual differences’.

AB - In recent years, substantial effort has gone into disentangling the genetic contribution to individual differences in behaviour (such as personality and temperament traits). Heritability estimates from twin and family studies, and more recently using whole genome approaches, suggest a substantial genetic component to these traits. However, efforts to identify the genes that influence these traits have had relatively little success. Here, we review current work investigating the heritability of individual differences in behavioural traits and provide an overview of the results from genome-wide association analyses of these traits to date. In addition, we discuss the implications of these findings for the potential applications of Mendelian randomization. This article is part of the theme issue ‘Diverse perspectives on diversity: multi-disciplinary approaches to taxonomies of individual differences’.

KW - Behavioural traits

KW - GWAS

KW - Heritability

KW - Mendelian randomization

KW - Personality

KW - Temperament

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U2 - 10.1098/rstb.2017.0162

DO - 10.1098/rstb.2017.0162

M3 - Article

VL - 373

JO - Philosophical Transactions B: Biological Sciences

JF - Philosophical Transactions B: Biological Sciences

SN - 0962-8436

IS - 1744

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ER -