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Imidazolium-tagged glycan probes for non-covalent labeling of live cells

Research output: Contribution to journalArticle

Original languageEnglish
Pages (from-to)4906-4909
Number of pages4
JournalChemical Communications
Volume52
Issue number27
DOIs
DateAccepted/In press - 7 Mar 2016
DatePublished (current) - 7 Apr 2016

Abstract

Selective, bioorthogonal and fast labeling of glycoconjugates in living cells is a major challenge for synthetic and cellular biology. Here we report the use imidazolium tagged-mannosamine derivative (ITag-Man) for the non-covalent, rapid and site-specific labeling of sialic acid containing glycoproteins using commercial N-nitrilotriacetate fluorescent reagents in a range of cell lines.

    Structured keywords

  • Bristol BioDesign Institute

    Research areas

  • SYNTHETIC BIOLOGY

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    Rights statement: This is the final published version of the article (version of record). It first appeared online via Royal Society of Chemistry at http://dx.doi.org/10.1039/C5CC10040B. Please refer to any applicable terms of use of the publisher.

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    Licence: CC BY

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