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Quantum dot-based probes for labeling and imaging of cells that express matrix metalloproteinases (MT-MMPs)

Research output: Contribution to journalArticle

Original languageEnglish
JournalACS Omega
DateAccepted/In press - 21 Jun 2018

Abstract

The practical synthesis of novel multivalent fluorescent Quantum Dot (QD)-based probes to target cellular matrix metalloproteinases (MT-MMPs) is reported. We show that these probes, which are decorated with a nanomolar water-soluble MMP inhibitor, can be used to label preferentially the surface of cancer cells that are known to express MMPs while no binding was observed on cells that do not.

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