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Remote, depth-based lung function assessment

Research output: Contribution to journalArticle

Original languageEnglish
Pages (from-to)1943-1958
Number of pages16
JournalIEEE Transactions on Biomedical Engineering
Volume64
Issue number8
Early online date1 Dec 2016
DOIs
DateAccepted/In press - 8 Oct 2016
DateE-pub ahead of print - 1 Dec 2016
DatePublished (current) - 15 Jul 2017

Abstract

Objective: We propose a remote, non-invasive approach to develop Pulmonary Function Testing (PFT) using a depth sensor. Method: After generating a point cloud from scene depth values, we construct a 3D model of the subject’s chest. Then, by estimating the chest volume variation throughout a sequence, we generate volume-time and flow-time data for two prevalent spirometry tests: Forced Vital Capacity (FVC) and Slow Vital Capacity (SVC). Tidal volume and main effort sections of volume-time data are analysed and calibrated separately to remove the effects of a subject’s torso motion. After automatic extraction of keypoints from the volume-time and flow-time curves, seven FVC (FVC, FEV1, PEF, FEF25%, FEF50%, FEF75% and FEF25−75%) and four SVC measures (VC, IC, TV and ERV) are computed and then validated against measures from a spirometer. A dataset of 85 patients (529 sequences in total), attending respiratory outpatient service for spirometry, was collected and used to evaluate the proposed method. Results: High correlation for FVC and SVC measures on intra-test and intra-subject measures between the proposed method and the spirometer. Conclusion: Our proposed depth-based approach is able to remotely compute 11 clinical PFT measures, which gives highly accurate results when evaluated against a spirometer on a dataset comprising 85 patients. Significance: Experimental results computed over an unprecedented number of clinical patients confirm that chest surface motion is linearly related to the changes in volume of lungs, which establishes the potential towards for an accurate, low-cost and remote alternative to traditional cumbersome methods, like spirometry.

    Research areas

  • Chest surface reconstruction, chest volume estimation, forced vital capacity (FVC), Kinect noise analysis, pulmonary function testing (PFT), spirometry, slow vital capacity (SVC), Digital Health

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